BioMatrix estriol is derived from an extraction of the steroidal backbone of the Mexican Wild Yam (Dioscorea villosa). It is bioidentical, meaning it has the same molecular structure as that produced naturally by the body.
Est-Adapt is an estriol-only formula, maximizing dosing options. Est-Adapt contains 0.5 mg per drop of estriol while the competing product contains 0.2 mg per drop. Other brands combine estriol and progesterone in the same formula, negating the opportunity for precision dosing. This creates limitations for addressing clinical needs and eliminates the option to use estriol on its own. For example, if a patient needs an additional 10 mg of estriol and is taking the combination product, they would be getting an extra 200 mg of progesterone, which is contraindicated in the majority of cases.